In the rapidly evolving business landscape shaped by Artificial Intelligence (AI), leaders must understand and embrace this technology to drive growth and success. The article highlights the importance of leaders acquiring a basic understanding of AI and data science, and developing six key skills to effectively lead AI transformation. These skills include strategic vision and innovation, change management, governance and risk management, interdisciplinary collaboration, critical thinking and problem-solving, and communication and leadership. By cultivating these skills, leaders can guide their organizations towards a prosperous, innovative future, and transform challenges into opportunities in the era of AI. Neodata is mentioned as a potential partner offering insights, technologies, and support for integrating AI into business strategies.